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HelpTest Code AAT Alpha-1-Antitrypsin, Serum
Additional Codes
Sunquest: AATM
EPIC: LAB810
Reporting Name
Alpha-1-Antitrypsin, SUseful For
Workup of individuals with suspected disorders such as familial chronic obstructive lung disease
Diagnosing alpha-1-antitrypsin deficiency
Testing Algorithm
For more information see Alpha-1-Antitrypsin-A Comprehensive Testing Algorithm.
Method Name
Nephelometry
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Special Instructions
Reference Values
100-190 mg/dL
Day(s) Performed
Monday through Friday
CPT Code Information
82103
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AAT | Alpha-1-Antitrypsin, S | 6771-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AAT | Alpha-1-Antitrypsin, S | 6771-0 |
Clinical Information
Alpha-1-antitrypsin (A1A) is the most abundant serum protease inhibitor, and it inhibits trypsin and elastin as well as several other proteases. The release of proteolytic enzymes from plasma onto organ surfaces and into tissue spaces results in tissue damage unless inhibitors are present. Congenital deficiency of A1A is associated with the development of emphysema at an unusually early age and with an increased incidence of neonatal hepatitis, usually progressing to cirrhosis.
For more information see Alpha-1-Antitrypsin-A Comprehensive Testing Algorithm.
Specimen Retention Time
14 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Report Available
1 to 3 daysForms
If not ordering electronically, complete, print, and send 1 of the following with the specimen:
-Gastroenterology and Hepatology Test Request (T728)
-General Request (T239)