Test Code HBNTP Hepatitis B Virus Surface Antigen Confirmation, Prenatal, Serum
Reporting Name
HBs Ag Confirmation Prenatal, SUseful For
Diagnosis of acute, recent, or chronic hepatitis B in prenatal patients
This test is not useful during the "window period" of acute hepatitis B (ie, after disappearance of hepatitis B virus surface antigen [HBsAg] and prior to appearance of HBs antibody).
This test is not suitable as stand-alone prenatal screening test of HBsAg status in pregnant women.
This test is not offered as a HBsAg screening or confirmatory test for blood donor specimens.
Method Name
Only orderable as a reflex. For more information see HBAGP / Hepatitis B Virus Surface Antigen Prenatal, Serum.
Electrochemiluminescence Immunoassay (ECLIA)
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
Serum SSTOrdering Guidance
Specimen Required
Only orderable as a reflex. For more information see HBAGP / Hepatitis B Virus Surface Antigen Prenatal, Serum.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Serum gel (red-top tubes are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions:
1. Centrifuge blood collection tube per manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).
2. Aliquot serum into a plastic vial.
Specimen Minimum Volume
0.7 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum SST | Frozen (preferred) | 90 days | |
Refrigerated | 6 days | ||
Ambient | 72 hours |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Special Instructions
Day(s) Performed
Monday through Saturday
CPT Code Information
87341
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HBNTP | HBs Ag Confirmation Prenatal, S | 7905-3 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
HBNTP | HBs Ag Confirmation Prenatal, S | 7905-3 |
Clinical Information
Hepatitis B virus (HBV) is a DNA virus that is endemic throughout the world. The infection is spread primarily through percutaneous contact with infected blood products (eg, blood transfusion, sharing of needles among injection drug users). The virus is found in various human body fluids, and it is known to be spread through oral and genital contact. HBV can be transmitted from mother to child during delivery through contact with blood and vaginal secretions, but it is not commonly transmitted transplacentally.
Hepatitis B surface antigen (HBsAg) is the first serologic marker appearing in the serum at 6 to 8 weeks following exposure to HBV. In acute infection, HBsAg usually disappears in 1 to 2 months after the onset of symptoms. Persistence of HBsAg for more than 6 months in duration indicates development of either a chronic carrier state or chronic HBV infection.
For more information see:
-Hepatitis B: Testing Algorithm for Screening, Diagnosis, and Management
-HBV Infection-Monitoring Before and After Liver Transplantation